Anatomy • The Splenic tissue develops from condensations of mesoderm in the dorsal mesogastrium. Spleen • Lymphatic organ connected to blood vascular system • Part of mononuclear phagocyte system. Spleen By: Muhammad Ramadan Ismael MBBCH Al-Azhar Faculty of Medicine, Cairo. Its long axis lies in the line of the tenth rib. First of all notice how the over all organization of the spleen looks like a BIG MESS. The marginal zone contained large … The spleen is the largest single mass of lymphatic tissue in the body. Spleen • situated principally in the left hypochondriac region, but its superior extremity extends into the epigastric region 3. structure of Spleen (2) This a low power image of the Spleen. The white pulp was characterized by the presence of large numbers of lymphatic nodules containing highly reactive germinal centers. Its average weight in the adult is about 150 gm. Histological structure of the spleen Stroma. Spleen. Full text Full text is available as a scanned copy of the original print version. Structure and function of the lymphatic system. Loading ... Add to tournament . The spleen combines the innate and adaptive immune system in a uniquely organized way. Normal Ultrasound (Equine) Histological section ©Nottingham Uni 2008 : The spleen lies vertically on the left side of the cranial abdomen. Actions. The spleen is enclosed in a capsule of fibrous and elastic tissue that extends into the parenchyma as trabeculae. Spleen tyrosine kinase is considered an attractive drug target for the treatment of allergic and antibody mediated autoimmune diseases. Many diseases and disorders of the spleen start with “Splen-” for example splenomegaly means enlargement of the spleen. This function, in combination with a highly organized lymphoid compartment, makes the spleen the most important organ for antibacterial and antifungal immune reactivity. Well-delineated cystic formations. The spleen is the largest lymphatic organ in the body. In many instances, the spleen enlarges as it performs its normal functions. Add to favorites 1 favs. In principle, the presence of an accessory spleen does not represent any health risks. Add to New Playlist. This function, in combination with a highly organized lymphoid compartment, makes the spleen the most important organ for antibacterial and antifungal immune reactivity. The spleen is surrounded by a thin capsule covered by peritoneum (mesothelial cells). The spleen is the largest secondary lymphoid organ in the body and, as such, hosts a wide range of immunologic functions alongside its roles in hematopoiesis and red blood cell clearance. Start studying 9. It is necessary to investigate the area of the spleen gates for revealing tubular structures in varicose veins. The pathologic process also may be acquired as a result of splenomegaly or ligamentous laxity, such as in pregnancy or muscular dystrophies. Rauscher spleen focus-forming virus contains functional gag and pol genes and a partially deleted env gene which is structurally related to the env genes of dual tropic murine leukemia viruses. Whereas the spleen growth was limited compared to the body growth in embryonic stages, the relative spleen weight increased 2.8 fold during the first 4 weeks post-hatching in quail. The spleen is divided by function and structure into the red pulp (RP) and white pulp (WP); in between these two regions is the marginal zone (MZ) in rodents and the perifollicular zone in humans (1, 2). The spleen is an organ the size of a fist found in the left upper quadrant (LUQ) of the abdomen, under the protection of the inferior thoracic cage. Game Statistics. Structure. Disturbance of spleen echostructure with or without splenomegaly. • Wedge shaped 2. Advertisement. Spleen histology slide (labeled) The spleen is a fist sized organ located in the left upper quadrant of the abdomen.It is the largest lymphoid organ and thus the largest filter of blood in the human body.The spleen has a unique location, embryological development and histological structure that differs significantly from other lymphoid organs. The spleen is located in the upper left abdominal cavity, just beneath the diaphragm, and posterior to the stomach.It is similar to a lymph node in shape and structure but it is much larger. The spleen is soft, highly vascular and dark purple in colour. The human spleen is surrounded by a capsule of dense connective tissue containing relatively little muscle and therefore incapable of the extensive contraction exhibited by the muscular capsule of the spleen in dogs and cats. The WP is the primary immunologic region of the spleen in both species; however, the WP makes up less than a quarter of splenic tissue. The physical organization of the spleen allows it to filter blood of pathogens and abnormal cells and facilitate … Structure and function of the immune system in the spleen Sci Immunol. An introduction to the histology of the spleen, as presented by the University of Rochester Pathology IT Program Many diseases and disorders of the spleen start with “Splen-” for example splenomegaly means enlargement of the spleen. Below is information about the structure and function of the canine spleen. Structure of human spleen icon. Structure and function of Spleen 1. Contents: • Anatomy • Physiology (Functions) • Splenic trauma • Splenomegaly 3. The structure of the spleen enables it to remove older erythrocytes from the circulation and leads to the efficient removal of blood-borne microorganisms and cellular debris. Author: Maria Yiallouros, erstellt am: 2016/11/30, Editor: Maria Yiallouros, English Translation: PD Dr. med. Gesche Tallen, Last modification: 2016/12/06 Table of contents. 10. We will tell you about the general structure of the spleen, how the spleen works in dogs, common diseases that affect the spleen and common diagnostic tests performed in dogs to evaluate the spleen. The "stuff" is first the Capsule, indicated by the black arrows that covers the whole organ. Today 's Points. Information on the anatomy of the spleen can be found on our sister website. The spleen is the largest organ of the lymphatic system.Located in the upper left region of the abdominal cavity, the spleen's primary function is to filter blood of damaged cells, cellular debris, and pathogens such as bacteria and viruses.Like the thymus, the spleen houses and aids in the maturation of immune system cells called lymphocytes. Fibrous and elastic tissue that extends into the epigastric region 3 stom­ach and the diaphragm lies vertically on the upper! 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